"An overview of the tobacco problem in India." Indian Journal of Medical and Paediatric Oncology 33.03 (2012): 139145
95% CI: 1.181.69, I 2 =33.5%)
Cotinine is more stable in the body, making it a good indicator of tobacco use, but nicotine can be converted into cotinine and back again, making the anabasine test essential for smokers who have quit with NRT
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Consequently, the brands with greater recognition are a major appealing factor
This fact known as the gateway effect of e-cigarettes for nicotine dependence and cigarette smoking is of particular importance, as the extensive body of literature provides unequivocal evidence that tobacco use in the form of cigarette smoking is the leading preventable cause of premature death and the major causal factor for ischemic heart disease, stroke, lung cancer, COPD and numerous other tobacco-related diseases that affect almost every organ in the human body (4, 10)